Мутагенез және мутация типтері. Биология, 10 сынып, дидактикалық материал.

Name:__________________________________ Date:_________________ Period:_______

• What can result when a mutation to DNA occurs?

• Explain the following types of gene mutations:
• Insertion –
• Deletion -
• Substitution –
• Point mutation –
• Frame-shift mutation –.
• A DNA segment is changed from-AAGTAG- to -AAATAG-.
• A DNA segment is changed from -AATTAGAAATAG- to -ATTAGAAATAG-. This is a(n)
• A DNA segment is changed from-GCTAGC- to -GCTATGC-. This is a(n)
• A DNA segment is changed from -AGTTGAAATAG- to -AGTTGAATAG-. This is a(n)
• A DNA segment is changed from -CCGTAAGAG- to - CCGGAAGAG -. This is a(n)
• A DNA segment is changed from -AATTAGAAATAG- to -ATTAGAAATAG-. This is a(n)
• Here are two related mRNA sequences: 5'UUUAGCGAGCAU3' and 5'UUUAGCCAUAAAAAAAA3'. How was the second sequence formed?
• A bacterium that was once able survive in a tryptophan-free environment is now unable to synthesize its own tryptophan. The bacterium is otherwise unaffected. Where is the most likely location for the mutation causing the change?

• What is a promoter?

• What type of mutation has occurred in the figure?

• What will be the result of the mutation in the figure?

• Using DNA sequencing, you discover that a bacterium has experienced a deletion mutation that removed three nucleotides. The bacterium appears completely unaffected in all its functions. Where is the mostly likely location for the mutation?

Gene Regulation – Can Hide Mutations Under certain condition

• An expressed gene is turned_____.
• Proteins that bind to _____________________ on DNA determine whether a gene is expressed.
• If a specific kind of protein is not continually used by a cell, the gene for that protein is ______

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